Imbue 800mg Embody CBD Lotion of Full Spectrum Hemp Extract

Rosemary, has been used as an antispasmodic, mild analgesic, to cure intercostal neuralgia, headaches, migraine, insomnia emotional upset, and depression. Different investigations have highlighted rosemary neuropharmacological properties as their main topics. Rosemary has significant antimicrobial, anti-inflammatory, anti-oxidant, anti-apoptotic, anti-tumorigenic, antinociceptive, and neuroprotective properties. Furthermore, it shows important clinical effects on mood, learning, memory, pain, anxiety, and sleep. The aim of the current work is to review the potential neuropharmacological effects of different rosemary extracts and its active constituents on nervous system disorders, their relevant mechanisms and its preclinical application to recall the therapeutic potential of this herb and more directions of future research projects. The data were gathered by searching the English articles in PubMed, Scopus, Google Scholar, and Web of Science. The keywords used as search terms were ‘Rosmarinus officinalis’, ‘rosemary’, ‘nervous system’, ‘depression’, ‘memory’, ‘Alzheimer’s disease’ ‘epilepsy’, ‘addiction’, ‘neuropathic pain’, and ‘disorders’. All kinds of related articles, abstracts and books were included. No time limitation was considered. Bothin vitroandin vivostudies were subjected to this investigation. This review authenticates that rosemary has appeared as a worthy source for curing inflammation, analgesic, anti-anxiety, and memory boosting. It also arranges new perception for further investigations on isolated constituents, especially carnosic acid, rosmarinic acid, and essential oil to find exquisite therapeutics and support drug discovery with fewer side effects to help people suffering from nervous system disorders. (1)

(1) Rosemary Skin Care: https://pmc.ncbi.nlm.nih.gov/articles/PMC7491497/

Skin Receptors from the ECS have been identified in the skin and systemic abuse of synthetic cannabinoids, and their analogs, have also been associated with the manifestation of dermatological disorders, indicating the effects of the ECS on cutaneous biology. In particular, cannabidiol (CBD), a non-psychoactive compound from the cannabis plant, has garnered significant attention in recent years for its anecdotal therapeutic potential for various pathologies, including skin and cosmetic disorders. Though a body of preclinical evidence suggests topical application of CBD may be efficacious for some skin disorders, such as eczema, psoriasis, pruritis, and inflammatory conditions, confirmed clinical efficacy and elucidation of underlying molecular mechanisms have yet to be fully identified. This article provides an update on the advances in CBD research to date and the potential areas of future exploration. (2)

(2) Skin Care: https://pmc.ncbi.nlm.nih.gov/articles/PMC7736837/

Topical application of CBD or THC containing products is not able to cause positive cannabinoid findings in the blood or urine. (3)

(3) Topicals Bloodstream: https://pubmed.ncbi.nlm.nih.gov/28122323/

Cannabidiol (CBD) is a potential therapeutic for pain management. Yet, there exists a dearth of studies of its tolerability and efficacy, especially in special populations. Former elite athletes are a special population both susceptible to chronic pain and also highly trained and attuned to assess medication tolerability concerns. The purpose of the present open-label pilot study was to assess the tolerability of CBD in this population.

Materials and methods

Retrospective analysis was conducted in deidentified data from 20 individuals who were all previously professional athletes in US/American football, track and field, or basketball, with careers ranging from 4 to 10 years. Participants received topical CBD (10 mg twice daily by controlled dispenser) for chronic pain resulting from acute lower extremity injuries. Assessments of tolerability and secondary analyses of pain, pain-related disability, and activities of daily living were collected by self-report over the 6-week study period. Data were analyzed by descriptive statistics, pairwise t-test, and linear regression. (4)

(4) CBD Topical Pain: https://pmc.ncbi.nlm.nih.gov/articles/PMC10061782/

Humans have utilised cannabis products in various forms throughout the recorded history. To date, more than 500 biologically active components have been identified in the plants of theCannabisgenus, amongst which more than 100 were classified as phytocannabinoids (exocannabinoids). The plant genusCannabisis a member of the plant family Cannabaceae, and there are three primary cannabis species which vary in their biochemical constituents:Cannabis sativa, Cannabis indicaandCannabis ruderalis. There has been a growing level of interest in research on the topical usage of a cannabis-based extract as a safer and more effective alternative to the usage of topical corticosteroids in treating some dermatoses. Together with the discovery of the cannabinoid receptors on the skin, it has been further illustrated that topical cannabis has anti-inflammatory, anti-itching, analgesics, wound healing and anti-proliferative effects on the skin. (5)

(5) CBD Topical for Inflammation: https://pmc.ncbi.nlm.nih.gov/articles/PMC9210160/

This is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitus, cardiovascular disease and cancer, its neuroprotective effect, and its effects on the gastrointestinal tract and other health complications related to these diseases. The results of the studies confirm that the anti-inflammatory, antiapoptotic, and pro-proliferative effects of “Vitis viniferaL.” seed extract reduce the level of oxidative stress and improve the overall lipid metabolism. (6)

(6) Grapeseed Oil: https://pmc.ncbi.nlm.nih.gov/articles/PMC7696942/