Imbue 3200mg CBD Salve of Full Spectrum of Hemp Extract for Horses, Farm and Ranch

Yes, The aim of this study was to evaluate the effect of oral cannabidiol (CBD) administration in addition to a conventional analgesic protocol on the clinical signs of 20 horses with mild joint osteoarthritis. The horses were randomly assigned to either the control group (C group) or the cannabidiol group (CBD group). Both groups were treated with phenylbutazone for 5 days. The CBD group received 0.03 mg/kg cannabidiol in hemp oil orally once daily for 14 days in addition to phenylbutazone treatment. All subjects were monitored for clinical parameters, oxidative status and blood counts. Pain and quality of life were also assessed using the Horse Chronic Pain Scale (HCPS). The CBD group showed a significant reduction in heart rate, respiratory rate, white blood cell count and oxidative stress (malondialdehyde lipid peroxidation). A significant reduction in HCPS scores was seen in both groups. Lower scores were recorded in the CBD group (3 med; range: 2/4) than in the C group (7 med; range: 4/10). The addition of a cannabidiol-based product to an analgesic protocol was well tolerated and showed positive effects on the treated subjects, improving their quality of life and pain relief. (1)

(1) CBD Topicals Equine: https://pmc.ncbi.nlm.nih.gov/articles/PMC10876772/

The therapeutic use of cannabidiol (CBD) is becoming increasingly popular, probably due to its perception as a natural treatment among pet owners. Several studies have shown that CBD reduces the production of inflammatory cytokines, thus helping to reduce inflammation in various tissues of the body and may have a calming effect on horses. Osteoarthritis (OA) is a progressive condition also known as degenerative joint disease. It is a major musculoskeletal disorder, causing reduced mobility and reluctance to move, affecting many species and is particularly prevalent in horses. These disorders (degenerative arthritis, osteoarthritis of the metacarpal/ metatarsophalangeal joint, interphalangeal joints, hoof disorders, vertebral lesions, kissing spines, periarticular osteophytes, synovitis) can lead to real complications with reduced welfare. Horses tend to be reluctant to be handled, unwilling to move and show signs of pain (lameness). (2)

(2) CBD for Horses Arthritis: https://pmc.ncbi.nlm.nih.gov/articles/PMC10876772/

Topical application of CBD or THC containing products is not able to cause positive cannabinoid findings in the blood or urine. (3)

(3) Topicals Bloodstream: https://pubmed.ncbi.nlm.nih.gov/28122323/

Cannabidiol (CBD) is a potential therapeutic for pain management. Yet, there exists a dearth of studies of its tolerability and efficacy, especially in special populations. Former elite athletes are a special population both susceptible to chronic pain and also highly trained and attuned to assess medication tolerability concerns. The purpose of the present open-label pilot study was to assess the tolerability of CBD in this population.

Materials and methods

Retrospective analysis was conducted in deidentified data from 20 individuals who were all previously professional athletes in US/American football, track and field, or basketball, with careers ranging from 4 to 10 years. Participants received topical CBD (10 mg twice daily by controlled dispenser) for chronic pain resulting from acute lower extremity injuries. Assessments of tolerability and secondary analyses of pain, pain-related disability, and activities of daily living were collected by self-report over the 6-week study period. Data were analyzed by descriptive statistics, pairwise t-test, and linear regression. (4)

(4) CBD Topical Pain: https://pmc.ncbi.nlm.nih.gov/articles/PMC10061782/

Humans have utilised cannabis products in various forms throughout the recorded history. To date, more than 500 biologically active components have been identified in the plants of theCannabisgenus, amongst which more than 100 were classified as phytocannabinoids (exocannabinoids). The plant genusCannabisis a member of the plant family Cannabaceae, and there are three primary cannabis species which vary in their biochemical constituents:Cannabis sativa, Cannabis indicaandCannabis ruderalis. There has been a growing level of interest in research on the topical usage of a cannabis-based extract as a safer and more effective alternative to the usage of topical corticosteroids in treating some dermatoses. Together with the discovery of the cannabinoid receptors on the skin, it has been further illustrated that topical cannabis has anti-inflammatory, anti-itching, analgesics, wound healing and anti-proliferative effects on the skin. (5)

(5) CBD Topical for Inflammation: https://pmc.ncbi.nlm.nih.gov/articles/PMC9210160/

Cannabidiol, better known as simply CBD, is one of the non-psychoactive compounds found in hemp. Its supplementation to horses is gaining in popularity as a potential alternative to conventional pharmaceutical treatments for a variety of conditions such as arthritis and anxiety. Despite potential advantages of CBD supplementation, it may have a negative impact on equine health and performance. More scientific research is needed to form recommendations for its use in horses; therefore, this study was designed to investigate supplementation of CBD oil over 28 days in 30 horses. Targeted levels of supplementation were to provide three levels for comparison (0.0 mg/kg, 0.75 mg/kg, or 1.50 mg/kg); however, the supplements collected during the study were analyzed to be substantially lower than targeted levels when tested at a verified testing facility (0.12 mg/kg and 0.13 mg/kg). At this level of supplementation, CBD oil was well-accepted, CBD was not detectible in blood samples, and blood chemistry parameters to assess liver and kidney function were not adversely affected as a result of supplementation. However, more research is needed to describe the discrepancy between formulated levels compared to tested levels of CBD supplements, in order to make recommendations for its application in the horse industry. (6)

(6) CBD for Horses in Competition: https://pmc.ncbi.nlm.nih.gov/articles/PMC9854761/